Lenovo ThinkPad E16 Gen 4 (AMD) 21Y4006NGE — Ryzen AI 7 345 / 32 GB / 1 TB SSD / 16" WUXGA / Win 11 Pro / Negro

The Lenovo ThinkPad E16 Gen 4 (AMD) in configuration 21Y4006NGE is a powerful 16-inch business laptop designed for modern professionals who need AI-enhanced performance, enterprise-grade security and all-day productivity. Powered by AMD's Ryzen AI 7 345 processor — a next-generation Zen 5-based chip with an integrated Neural Processing Unit (NPU) enabling Copilot+ PC experiences — it delivers exceptional multitasking capability in a slim, lightweight chassis weighing just 1.77 kg.

Advantages

The AMD Ryzen AI 7 345 processor (6 cores, 12 threads, up to 5.0 GHz boost) provides outstanding performance for office applications, development tasks and content creation, while the integrated AMD Radeon 890M graphics handles everyday visuals and light creative work with ease. A generous 32 GB of DDR5 memory ensures smooth parallel workloads, and the 1 TB PCIe NVMe SSD delivers rapid storage for projects and data. The 16-inch WUXGA (1920 x 1200) IPS display with a 16:10 aspect ratio offers crisp, comfortable viewing across long work sessions. Wi-Fi 7 and Bluetooth 5.4 provide fast, reliable wireless connectivity, and the pre-installed Windows 11 Pro readies the machine for business and enterprise deployment from day one.

Suitable for

• Business professionals and enterprise users needing AI-accelerated productivity with Copilot+ PC features
• Developers, analysts and knowledge workers handling large codebases, datasets or office suites
• Remote and hybrid workers requiring a lightweight, durable laptop with strong security features
• IT departments deploying standardised Lenovo ThinkPad business laptops at scale

Key specifications

• Brand: Lenovo
• Model: ThinkPad E16 Gen 4 (AMD)
• MPN: 21Y4006NGE
• EAN: 199276765710
• Type: Laptop (Copilot+ PC)
• Processor: AMD Ryzen AI 7 345, 6 cores, 12 threads, up to 5.0 GHz boost, Zen 5 architecture, integrated NPU
• Graphics: Integrated AMD Radeon 890M
• Memory: 32 GB DDR5-5600
• Storage: 1 TB M.2 PCIe NVMe SSD
• Display: 16" (40.6 cm) WUXGA 1920 x 1200 IPS, 16:10, anti-glare, non-touch
• Operating system: Windows 11 Pro (64-bit)
• Wireless: Wi-Fi 7 (802.11be), Bluetooth 5.4
• Wired networking: Gigabit Ethernet (RJ-45)
• Ports: USB-C with Power Delivery and DisplayPort, USB-A 3.2, HDMI 2.1, 3.5 mm combo audio jack
• Webcam: FHD 1080p with privacy shutter
• Security: Fingerprint reader, TPM 2.0, Kensington lock slot
• Keyboard: Backlit, spill-resistant
• Battery: 64 Wh Li-Ion
• Colour: Black
• Dimensions: 356 x 249 x 21.15 mm
• Weight: approx. 1.77 kg

How to use

Power on and complete the Windows 11 Pro initial setup, then sign in with a Microsoft or Azure AD account to access Copilot+ AI features immediately. Connect via Wi-Fi 7 or the RJ-45 Gigabit Ethernet port, install any required business software or MDM profile, and use the fingerprint reader for fast, secure Windows Hello sign-in.

Recommendations

For businesses standardising on AMD-based ThinkPad hardware, the E16 Gen 4 offers an excellent balance of AI performance, screen real estate and value — pair it with a Lenovo ThinkPad USB4 dock to extend connectivity at a fixed desk without sacrificing portability on the go.